Symposia
Technology/Digital Health
Jennifer L. L. Greenberg, Psy.D.
Psychologist/Assistant Professor
Massachusetts General Hospital/Harvard Medical School
Boston, Massachusetts, United States
Hilary Weingarden, Ph.D. (she/her/hers)
Psychologist/Assistant Professor
Massachusetts General Hospital
Boston, Massachusetts, United States
Susanne S. Hoeppner, Ph.D., M.Ap.Stat.
Biostatistician epidemiologist
Massachusetts General Hospital
Boston, Massachusetts, United States
Rebecca Berger-Gutierrez, B.A.
Clinical Research Coordinator
MGH/Harvard Medical School
Boston, Massachusetts, United States
Dalton Klare, M.A., M.S. (he/him/his)
Data Analyst/Clinical Data Manager
Massachusetts General Hospital
Boston, Massachusetts, United States
Ivar Snorrason, PhD (he/him/his)
Staff Psychologist
Massachusetts General Hospital / Harvard Medical School
Boston, Massachusetts, United States
Omar Costilla-Reyes, PhD
Research Scientist
MIT
Cambridge, Massachusetts, United States
Morgan Talbot, MD/PhD Candidate
Graduate Student
MIT
Cambridge, Massachusetts, United States
Katharine Daniel, MA
Clinical Fellow
MGH/Harvard Medical School
Boston, Massachusetts, United States
Rachel Vanderkruik, PhD
Psychologist
MGH/Harvard Medical School
Boston, Massachusetts, United States
Armando Solar-Lezama, PhD
Professor
MIT
Cambridge, Massachusetts, United States
Oliver Harrison, MA, MBBS, MPH
CEO
Koa Health
Barcelona, Catalonia, Spain
Sabine Wilhelm, Ph.D. (she/her/hers)
Professor, HMS; Chief of Psychology, MGH; Director, Center for Digital Mental Health, MGH
Harvard Medical School
Boston, Massachusetts, United States
Background: Body dysmorphic disorder (BDD) is a severe, chronic disorder if untreated. Smartphone cognitive behavioral therapy (CBT) for BDD is efficacious and can reduce key treatment barriers (e.g., lack of clinicians, cost, stigma). While promising, little is known about who is more or less likely to benefit from this approach.
Methods: This is a secondary data analysis of a randomized, waitlist-controlled trial of smartphone CBT for BDD. Participants (N=80) were recruited nationally and randomized to receive a 12-week, coach-guided CBT for BDD app, either immediately or after a 12-week waitlist. The main outcome for this analysis was BDD severity (BDD-YBOCS) over time (baseline, week 6, week 12) during the active app use phase in each randomized group (n=74). Secondary outcomes included treatment response (>30% reduction in BDD-YBOCS) and remission (total BDD-YBOCS ≤16) at end-of-treatment.
Results: Immediate (vs. delayed) CBT predicted better outcomes (symptom improvement), as did gender identity (symptom improvement), higher baseline treatment credibility and expectancy (response, remission), lower baseline BDD severity (remission), and sexual minority status (vs. heterosexual; response, remission). Limitations: Limitations include the relatively small sample, drop-out rate of 22%, and limited gender and racial-ethnic diversity.
Conclusions: These results highlight a potential advantage of smartphone CBT in historically marginalized populations, and the importance of efforts to hasten treatment access, bolster confidence in the treatment at treatment onset, and develop stratified care models to optimize treatment allocation and efficacy.