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Evaluation ViewAttendees 2

Treatment - CBT
Symposia

Symposium 85 - Neuroscience based approaches to integrating CBT and not-exclusively-psychological treatments

Saturday, November 16, 2024
12:30 PM – 2:00 PM EST
Location: 309/310, Level 3, Downtown Marriott
CE: 1.5

Keywords: CBT, Neuroscience, Neurocognitive Therapies
Level of Familiarity: Moderate
Recommended Readings: Strawbridge R, Carter B, Marwood L, et al. Augmentation therapies for treatment-resistant depression: systematic review and meta-analysis. British Journal of Psychiatry. 2019;214(1):42-51. doi:10.1192/bjp.2018.233,   Patterson, B. & Ameringen, M.V. (2016). Augmentation strategies for treatment-resistant anxiety disorders: A systematic review and meta-analysis. Depression & Anxiety, 33(8), 728-736,   Siegle, G.J., Ghinassi, F., Thase, M.E. (2007). Neurobehavioral therapies in the 21st century: Summary of an emerging field and an extended example of Cognitive Control Training for depression. Cognitive Therapy and Research, 31, 235-262. Doi:10.1007/s10608-006-9118-6,   Compere, L., Siegle, G.J.*, Riley, E., Lazzaro, S., Strege, M., Pacoe, B., Canovali, G., Barb, S., Huppert, T., Young, K. (2023). Enhanced efficacy of CBT following augmentation with amygdala rtfMRI neurofeedback in depression. Journal of Affective Disorders, 339, 495-501. PMID: 37459978; PMCID: PMC10530481. doi: 10.1016/j.jad.2023.07.063.,   Huang, X., Funsch, K.M., Park, E.C. et al. Longitudinal studies support the safety and ethics of virtual reality suicide as a research method. Sci Rep 11, 9653 (2021). https://doi.org/10.1038/s41598-021-89152-0

Core principles of CBT involve recognition of feelings and being able to identify thoughts and memories relevant to those feelings. When these competences are at deficit, suitability for CBT has been questioned. As such, augmenting CBT with technologies and agents which bolster these domains may help to enhance CBT outcomes. That said, the track-record for non-mechanistically derived augmentations for CBT has been variable with augmentations rarely addressing specific aspects of CBT that are at deficit. Here, we describe technologies, derived and supported using a neuroscience framework to address these domains, and their effects on CBT outcomes, to inform both researchers and clinicians about current frontiers in enhancing CBT. 

Technologies for enhancing thought/feeling identification will include enhancement of interoception using vibration synchronized to physiological signals (Siegle), enhancement of autobiographical memory using real-time fMRI-based neurofeedback (Compere), enhancement of social information processing using intranasal oxytocin (Grennan), and enhancement of realistic exposure experiences using virtual reality (Brown). Each presenter will describe the domain they are addressing, the neural mechanisms their technology targets, and will present data on changes in the domain as well as clinical changes observed using the proposed technology. They will critically comment on the potential for and limitations of generalization of these technologies to diverse populations given the current state of knowledge; the relative dearth of neuroscience and pharmacological research in minoritized populations will specifically be addressed. The current chair of ABCT's Neurocognitive Therapies and Translational Research Special Interest Group (Strege) will provide integrative discussion in the context of the extent to which mechanistic interventions can make a practical difference.

Learning Objectives:

At the end of this session, the learner will be able to:
  1. Name ways in which CBT can be augmented using technologies that do not involve talking
  2. Describe the neural basis for technologies that can augment psychotherapy
  3. Explain limitations of CBT augmentation research for minoritized populations and steps being taken to address this issue
  4. Discuss easy in which individual differences may lead to choosing different augmentation strategies for CBT
  5. Describe how neuroscience can inform treatment development by targeting specific mechanisms

Presentations:

  • 12:30 PM – 2:00 PM EST
    (SYM 85) Augmenting Mindfulness to Enhance Interoception with Breath-synchronized Vibration

    Speaker: Greg J. Siegle, Ph.D. (he/him/his) – University of Pittsburgh School of Medicine

    Co-author: Rebecca Krawczak, B.S. (she/her/hers) – Wayne State University

    Co-author: Alfonsina Guelfo, B.S. (she/her/hers) – Emory University

    Co-author: Robert Krafty, Ph.D. (he/him/his) – Emory University

    Co-author: Vishwadeep Ahluwalia, Ph.D. (he/him/his) – Georgia Institute of Technology

    Co-author: Negar Fani, Ph.D. (she/her/hers) – Emory University

  • 12:30 PM – 2:00 PM EST
    (SYM 85) Learning Safety from Others with Intranasal Oxytocin in Social Anxiety Disorder

    Speaker: Gillian Grennan, B.S. (she/her/hers) – University of Washington

    Co-author: Emily Iannazzi, B.A. – University of Washington, Seattle

    Co-author: Yuchen Zhao, M.S. – University of Washington, Seattle

    Co-author: Maggie Sarkisova, None – University of Washington, Seattle

    Co-author: Ken Kavin, B.S. (he/him/his) – University of Washington

    Co-author: Nathan Sackett, M.D., M.S. (he/him/his) – University of Washington

    Co-author: Armita Golkar, Ph.D. (she/her/hers) – Stockholm University

    Co-author: Andreas Olsson, Ph.D. (he/him/his) – Karolinska Institutet

    Co-author: Angela Fang, Ph.D. – University of Washington, Seattle

  • 12:30 PM – 2:00 PM EST
    (SYM 85) Enhanced Outcomes for CBT Following Augmentation with Amygdala Rt-fmri Neurofeedback in Depression

    Speaker: Laurie Compere, Ph.D. (she/her/hers) – University of Pittsburgh

    Co-author: Greg J. Siegle, Ph.D. (he/him/his) – University of Pittsburgh School of Medicine

    Co-author: Emily Riley, B.S. (she/her/hers) – University of Pittsburgh

    Co-author: Sair Lazzaro, B.S. (they/them/theirs) – George Washington University

    Co-author: Marlene V. Strege, Ph.D. (she/her/hers) – University of Pittsburgh School of Medicine

    Co-author: Elizabeth Pacoe, Ph.D. (she/her/hers) – Tripp Psychiatry

    Co-author: Gia Canovali, LCSW (she/her/hers) – The Center for OCD and Anxiety

    Co-author: Scott Barb, LSW (he/him/his) – University of Pittsburgh

    Co-author: Theodore Huppert, Ph.D. (he/him/his) – University of Pittsburgh

    Co-author: Kymberly Young, Ph.D. (she/her/hers) – University of Pittsburgh

  • 12:30 PM – 2:00 PM EST
    (SYM 85) Virtual Reality for Suicidal Behavior

    Speaker: Sarah L. Brown, Ph.D. – University of Pittsburgh School of Medicine

    Co-author: Greg J. Siegle, Ph.D. (he/him/his) – University of Pittsburgh School of Medicine

    Co-author: Lori Scott, Ph.D. – University of Pittsburgh School of Medicine