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,Danielle Moskow Diamond, Ph.D. (she/her/hers)
Montefiore Medical Center/Albert Einstein College of Medicine
Boston, Massachusetts, United States
Andrew Curreri, Ph.D. (he/him/his)
Icahn School of Medicine at Mount Sinai
Astoria, New York, United States
Joshua Curtiss, M.A., Ph.D.
Assistant Professor in Applied Psychology
Northeastern University
Boston, Massachusetts, United States
Joseph Carpenter, Ph.D. (he/him/his)
Postdoctoral Fellow
VA Boston / National Center for PTSD
Boston, Massachusetts, United States
Danielle Moskow Diamond, Ph.D. (she/her/hers)
Montefiore Medical Center/Albert Einstein College of Medicine
Boston, Massachusetts, United States
Kathy Shekhtman, Ph.D. (she/her/hers)
NYU Langone Medical Center / Steven A. Cohen Military Family Center
Flushing, New York, United States
Post-traumatic stress disorder (PTSD) is a severe mental illness that can have widespread, multi-faceted effects (Sayers et al., 2009; Schnurr et al., 2009). Lifetime PTSD prevalence in the U.S. is currently 6.1% (Chou et al., 2016). Despite the establishment of empirically supported interventions for PTSD, as many as 30-50% of patients who receive such treatments retain a diagnosis of PTSD (APA, 2017). On account of the impact of PTSD and trauma- and stress-related disorders, this symposium will cover two areas of innovative research that can help address such suboptimal treatment outcomes: 1) advances in precision medicine and analytical approaches that can help to identify who is most likely to benefit from a given treatment, and 2) novel intervention approaches that address previously underemphasized treatment targets underlying trauma- and stress-related psychopathology.
The first two talks use advanced modeling techniques to predict a variety of important outcomes of existing evidence-based treatments for PTSD - namely cognitive processing therapy and prolonged exposure.
The first presentation will relay how elastic net machine learning can predict primary and secondary treatment outcomes for patients with PTSD receiving either prolonged exposure (PE) therapy or cognitive processing therapy (CPT) across four clinical trials (N=482). The study will highlight how machine learning can predict distinct outcomes with differential success. The second presentation used a machine learning approach to study whether dropout could be predicted from baseline clinical and demographic variables when modeling White and Black patients separately, and whether predictors were similar across racial groups.
The second two talks focus on novel approaches to treating trauma and stress symptoms that target less commonly addressed processes, namely loneliness and positive affect.
The third presentation will address a new group treatment approach, called meaning-centered group-based CBT (MC-CBT). MC-CBT is a 16 week treatment that helps address themes of loneliness and meaninglessness in individuals who have completed a course of CBT for trauma.
The fourth presentation will share results from a six-session, novel intervention called Positive Processes and Transition to Health (PATH). This treatment is grounded in evidence-based principles that directly target symptoms of PTSD and/or depression following a significant and destabilizing stressor by influencing three key, transdiagnostic processes implicated in the onset, maintenance, and relapse of these disorders. Researchers examined how the addition of positive event reminiscing targets anhedonia and positive affect, which are key features of PTSD and depression, during this brief treatment.
Together these studies will shed light on alternative approaches to traditional CBT for trauma and PTSD, as well as provide information about treatment outcome that will be beneficial for therapists, researchers and patients.
Speaker: Joshua Curtiss, M.A., Ph.D. – Northeastern University
Co-author: Joseph K. Carpenter, Ph.D. (he/him/his) – VA Boston / National Center for PTSD
Co-author: Patricia A. Resick, ABPP, Ph.D. (she/her/hers) – Duke University School of Medicine
Co-author: Tara Galovski, Ph.D. – VA National Center for PTSD, Boston University School of Medicine
Speaker: Joseph K. Carpenter, Ph.D. (he/him/his) – VA Boston / National Center for PTSD
Co-author: Joshua Curtiss, M.A., Ph.D. – Northeastern University
Co-author: Patricia A. Resick, ABPP, Ph.D. (she/her/hers) – Duke University School of Medicine
Co-author: Tara Galovski, Ph.D. – VA National Center for PTSD, Boston University School of Medicine
Speaker: Danielle Moskow Diamond, Ph.D. (she/her/hers) – Montefiore Medical Center/Albert Einstein College of Medicine
Co-author: Amanda W. Baker, PhD (she/her/hers) – Massachusetts General Hospital/Harvard Medical Center
Co-author: Nicole J. LeBlanc, PhD (she/her/hers) – Massachusetts General Hospital/Harvard Medical Center
Co-author: Benjamin W. Bellet, PhD (he/him/his) – Massachusetts Mental Health Center/Beth Israel Deaconess Medical Center
Co-author: Emily Mintz, B.A. – Massachusetts General Hospital
Co-author: Jonah N. Cohen, PhD (he/him/his) – Massachusetts General Hospital/Harvard Medical Center
Speaker: Kathy Shekhtman, Ph.D. (she/her/hers) – NYU Langone Medical Center / Steven A. Cohen Military Family Center
Co-author: Kathy Shekhtman, Ph.D. (she/her/hers) – NYU Langone Medical Center / Steven A. Cohen Military Family Center
Co-author: Alice E. Coyne, Ph.D. (she/her/hers) – American University
Co-author: Adele M. Hayes, Ph.D. (she/her/hers) – University of Delaware
Co-author: Lori A. Zoellner, Ph.D. – University of Washington
Co-author: Norah C. Feeny, Ph.D. – Case Western Reserve University